Increased Occurrence of Cutaneous Leiomyomas and Dermatofibromas in Patients with Uterine Leiomyomas without Fumarate Hydratase Gene Mutations

• Main Authors: Elena Campione (Author), Monia Di Prete (Author), Gaetana Costanza (Author), Andrea Saggini (Author), Sara Agostinelli (Author), Alessandro Terrinoni (Author), Federica Centofanti (Author), Maria Cristina Rapanotti (Author), Luca Bianchi (Author), Amedeo Ferlosio (Author), Maria Giovanna Scioli (Author), Augusto Orlandi (Author)
• Format: Book
• Published: MDPI AG, 2023-08-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Leiomyomas are smooth muscle-derived benign neoplasms that can affect all organs, most frequently in the uterus. Fumarate hydratase gene (FH) mutation is characterised by an autosomal dominant disease with increased occurrence of renal tumours, but also by cutaneous (CLs) and uterine leiomyomas (ULs...