Copper interactions with DNA of chromatin and its role in neurodegenerative disorders

Copper interactions with DNA of chromatin and its role in neurodegenerative disorders

In this study, we have demonstrated the conformational changes to DNA induced by abnormal interactions of copper using circular dichroism, in combination with UV-absorbance and fluorescence spectroscopy. Results confirm that binding of copper to bases of DNA in chromatin is concentration dependent....

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Main Authors: M. Govindaraju (Author), H.S. Shekar (Author), S.B. Sateesha (Author), P. Vasudeva Raju (Author), K.R. Sambasiva Rao (Author), K.S.J. Rao (Author), A.J. Rajamma (Author)
Format: Book
Published: Elsevier, 2013-10-01T00:00:00Z.
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