C4b-Binding Protein and Factor H Inhibit Inflammasome Activation during Group A Streptococci Infection in Human Cells.

C4b-Binding Protein and Factor H Inhibit Inflammasome Activation during Group A Streptococci Infection in Human Cells.

Introduction. Streptococcus pyogenes (Group A Streptococcus; GAS) is a pathogen that causes over half a million deaths annually worldwide. Human immune cells respond to GAS infection by activating the NLRP3 inflammasome that leads to pro-inflammatory cytokines release which acts to control infection...

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Main Authors: Serena Bettoni (Author), Mateusz Dziedzic (Author), Damien Bierschenk (Author), Maja Chrobak (Author), Michal Magda (Author), Maisem Laabei (Author), Ben C. King (Author), Kristian Riesbeck (Author), Anna M. Blom (Author)
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Published: Karger Publishers, 2024-11-01T00:00:00Z.
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3rd Floor Main Library

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