Pharmacogenomics as a Tool to Limit Acute and Long-Term Adverse Effects of Chemotherapeutics: An Update in Pediatric Oncology

• Main Authors: Emma C. Bernsen (Author), Melanie M. Hagleitner (Author), Theodorus W. Kouwenberg (Author), Lidwien M. Hanff (Author)
• 格式: 图书
• 出版: Frontiers Media S.A., 2020-08-01T00:00:00Z.
• 主题: article
• 在线阅读: Connect to this object online.

In the past decades, new cancer treatments have been introduced in pediatric oncology leading to improvement in clinical outcomes and survival rates. However, due to inter-individual differences, some children experience severe chemotherapy-induced toxicities or a poor clinical outcome. An explanati...