The heterogeneity and drug resistance of malignant cells and intercellular communication of microenvironment in osteosarcoma: Based on single‐cell analysis

• Main Authors: Haonan Ma (Author), Xiaoyu Wang (Author), Jiayi Zhao (Author), Jiayi Wang (Author), Qian Li (Author), Jinrong Liang (Author), Xiaomin Ding (Author), Yawen Zhang (Author), Yan Zhou (Author), Haiyan Hu (Author)
• Format: Book
• Published: Wiley, 2023-06-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract Background Osteosarcoma (OS) is a prevalent bone cancer characterized by its aggressive nature, which often metastasizes to the lungs and contributes to a poor prognosis. Treatment progress has been hindered by drug resistance, distant metastases, and significant patient heterogeneity. Howe...