SETD4 Confers Cancer Stem Cell Chemoresistance in Nonsmall Cell Lung Cancer Patients via the Epigenetic Regulation of Cellular Quiescence

• Principais autores: Yuehong Wang (Autor), Yuman Yu (Autor), Weijun Yang (Autor), Linying Wu (Autor), Yaoshun Yang (Autor), Qianyun Lu (Autor), Jianying Zhou (Autor)
• Formato: Livro
• Publicado em: Hindawi Limited, 2023-01-01T00:00:00Z.
• Assuntos: article
• Acesso em linha: Connect to this object online.

Increasing evidence indicates that quiescent cancer stem cells (CSCs) are a root cause of chemoresistance. SET domain-containing protein 4 (SETD4) epigenetically regulates cell quiescence in breast cancer stem cells (BCSCs), and SETD4-positive BCSCs are chemoradioresistant. However, the role of SETD...