Maternal Antibody-Mediated Disease Enhancement in Type I Interferon-Deficient Mice Leads to Lethal Disease Associated with Liver Damage.

• Main Authors: Julia María Martínez Gómez (Author), Li Ching Ong (Author), Jian Hang Lam (Author), Siti Amanlina Binte Aman (Author), Eshele Anak Libau (Author), Pei Xuan Lee (Author), Ashley L St John (Author), Sylvie Alonso (Author)
• Format: Book
• Published: Public Library of Science (PLoS), 2016-03-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Epidemiological studies have reported that most of the severe dengue cases occur upon a secondary heterologous infection. Furthermore, babies born to dengue immune mothers are at greater risk of developing severe disease upon primary infection with a heterologous or homologous dengue virus (DENV) se...