A joint transcriptional regulatory network and protein activity inference analysis identifies clinically associated master regulators for biliary atresia

• Principais autores: Panpan Sun (Autor), Manhuan Xiao (Autor), Huadong Chen (Autor), Zhihai Zhong (Autor), Hong Jiang (Autor), Xuyang Feng (Autor), Zhenhua Luo (Autor)
• Formato: Livro
• Publicado em: Frontiers Media S.A., 2022-11-01T00:00:00Z.
• Assuntos: article
• Acesso em linha: Connect to this object online.

Biliary atresia (BA) is a devastating cholangiopathy in neonate. Transcription factors (TFs), a type of master regulators in biological processes and diseases, have been implicated in pathogenesis of BA. However, a global view of TFs and how they link to clinical presentations remain explored. Here,...