Design, synthesis, in vitro potent antiproliferative activity, and kinase inhibitory effects of new triarylpyrazole derivatives possessing different heterocycle terminal moieties

A new series of triarylpyrazole derivatives having different heterocycle terminal groups have been designed and synthesised. Compounds 1h-j and 1l exhibited the highest mean percentage inhibition against the 58 cancer cell lines at a concentration of 10 μM, and thus were next examined in 5-dose test...

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Bibliographic Details
Main Authors: Mahmoud M. Gamal El-Din (Author), Mohammed I. El-Gamal (Author), Mohammed S. Abdel-Maksoud (Author), Kyung Ho Yoo (Author), Chang-Hyun Oh (Author)
Format: Book
Published: Taylor & Francis Group, 2019-01-01T00:00:00Z.
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