Profiling the Site of Protein CoAlation and Coenzyme A Stabilization Interactions

• Main Authors: Maria-Armineh Tossounian (Author), Maria Baczynska (Author), William Dalton (Author), Charlie Newell (Author), Yilin Ma (Author), Sayoni Das (Author), Jonathan Alexis Semelak (Author), Dario Ariel Estrin (Author), Valeriy Filonenko (Author), Madia Trujillo (Author), Sew Yeu Peak-Chew (Author), Mark Skehel (Author), Franca Fraternali (Author), Christine Orengo (Author), Ivan Gout (Author)
• Format: Book
• Published: MDPI AG, 2022-07-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Coenzyme A (CoA) is a key cellular metabolite known for its diverse functions in metabolism and regulation of gene expression. CoA was recently shown to play an important antioxidant role under various cellular stress conditions by forming a disulfide bond with proteins, termed CoAlation. Using anti...