Human Mesenchymal Stem Cell Therapy Reverses Su5416/Hypoxia-Induced Pulmonary Arterial Hypertension in Mice

• Main Authors: Allan K. N. Alencar (Author), Pedro M. Pimentel-Coelho (Author), Guilherme C. Montes (Author), Marina de M. C. da Silva (Author), Luiza V. P. Mendes (Author), Tadeu L. Montagnoli (Author), Ananssa M. S. Silva (Author), Juliana Ferreira Vasques (Author), Paulo Henrique Rosado- (Author), Bianca Gutfilen (Author), Valéria do M. N. Cunha (Author), Aline G. M. Fraga (Author), Patrícia M R e Silva (Author), Marco Aurélio Martins (Author), Tatiana Paula Teixeira Ferreira (Author), Rosalia Mendes-Otero (Author), Margarete M. Trachez (Author), Roberto T. Sudo (Author), Gisele Zapata-Sudo (Author)
• Format: Book
• Published: Frontiers Media S.A., 2018-12-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Aims: Pulmonary arterial hypertension (PAH) is a disease characterized by an increase in pulmonary vascular resistance and right ventricular (RV) failure. We aimed to determine the effects of human mesenchymal stem cell (hMSC) therapy in a SU5416/hypoxia (SuH) mice model of PAH.Methods and Results:...