Tutorial on model selection and validation of model input into precision dosing software for model‐informed precision dosing

• Main Authors: Zachary L. Taylor (Author), Ethan A. Poweleit (Author), Kelli Paice (Author), Katherine M. Somers (Author), Kathryn Pavia (Author), Alexander A. Vinks (Author), Nieko Punt (Author), Tomoyuki Mizuno (Author), Sonya Tang Girdwood (Author)
• Format: Book
• Published: Wiley, 2023-12-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract There has been rising interest in using model‐informed precision dosing to provide personalized medicine to patients at the bedside. This methodology utilizes population pharmacokinetic models, measured drug concentrations from individual patients, pharmacodynamic biomarkers, and Bayesian e...