Capsaicin ameliorate pulmonary fibrosis via antioxidant Nrf-2/ PPAR- γ pathway activation and inflammatory TGF-β1/ NF-κB/COX II pathway inhibition

• Main Authors: Wesam H. Abdulaal (Author), Hani Z. Asfour (Author), Nawal Helmi (Author), Hadeel Al Sadoun (Author), Basmah Eldakhakhny (Author), Nabil A. Alhakamy (Author), Hani Mohammed Alqarni (Author), Saeed Ali Mohammed Alzahrani (Author), Mohamed A. El-Moselhy (Author), Sara S. Sharkawi (Author), Esam Mohamed Aboubakr (Author)
• Formato: Libro
• Publicado: Frontiers Media S.A., 2024-02-01T00:00:00Z.
• Subjects: article
• Acceso en liña: Connect to this object online.

Bleomycin is an effective antibiotic with a significant anticancer properties, but its use is limited due to its potential to induce dose-dependent pulmonary fibrosis. Therefore, this study aimed to assess the therapeutic potential of Capsaicin as an additional treatment to enhance patient tolerance...