Capsaicin ameliorate pulmonary fibrosis via antioxidant Nrf-2/ PPAR- γ pathway activation and inflammatory TGF-β1/ NF-κB/COX II pathway inhibition

Capsaicin ameliorate pulmonary fibrosis via antioxidant Nrf-2/ PPAR- γ pathway activation and inflammatory TGF-β1/ NF-κB/COX II pathway inhibition

Bleomycin is an effective antibiotic with a significant anticancer properties, but its use is limited due to its potential to induce dose-dependent pulmonary fibrosis. Therefore, this study aimed to assess the therapeutic potential of Capsaicin as an additional treatment to enhance patient tolerance...

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Main Authors: Wesam H. Abdulaal (Author), Hani Z. Asfour (Author), Nawal Helmi (Author), Hadeel Al Sadoun (Author), Basmah Eldakhakhny (Author), Nabil A. Alhakamy (Author), Hani Mohammed Alqarni (Author), Saeed Ali Mohammed Alzahrani (Author), Mohamed A. El-Moselhy (Author), Sara S. Sharkawi (Author), Esam Mohamed Aboubakr (Author)
Format: Book
Published: Frontiers Media S.A., 2024-02-01T00:00:00Z.
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