Naringin attenuates fructose-induced NAFLD progression in rats through reducing endogenous triglyceride synthesis and activating the Nrf2/HO-1 pathway

• Main Authors: Sirinat Pengnet (Author), Phinsuda Sumarithum (Author), Nuttaphong Phongnu (Author), Sakdina Prommaouan (Author), Napapas Kantip (Author), Ittipon Phoungpetchara (Author), Wachirawadee Malakul (Author)
• Format: Book
• Published: Frontiers Media S.A., 2022-12-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Background: Excessive fructose consumption causes hepatic lipid accumulation via increased triglyceride (TG) synthesis, leading to the development and progression of non-alcoholic fatty liver disease (NALFD). Naringin, a flavanone glycoside found in citrus fruit, has antioxidant and hypolipidemic pr...