Herbal Medicine AC591 Prevents Oxaliplatin-Induced Peripheral Neuropathy in Animal Model and Cancer Patients

• Main Authors: Xiaolan Cheng (Author), Jiege Huo (Author), Dawei Wang (Author), Xueting Cai (Author), Xiaoyan Sun (Author), Wuguang Lu (Author), Yang Yang (Author), Chunping Hu (Author), Xiaoning Wang (Author), Peng Cao (Author)
• Format: Book
• Published: Frontiers Media S.A., 2017-06-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Oxaliplatin is clinically compelling because of severe peripheral neuropathy. The side effect can result in dosage reductions or even cessation of chemotherapy, and no effective treatments are available. AC591 is a standardized extract of Huangqi Guizhi Wuwu decoction, an herbal formula recorded in...