Structural determinants for binding to angiotensin converting enzyme 2 (ACE2) and angiotensin receptors

• Váldodahkkit: Daniel eClayton (Dahkki), Iresha eHanchapola (Dahkki), Walter Glen Thomas (Dahkki), Robert eWiddop (Dahkki), Alexander Ian Smith (Dahkki), Patrick ePerlmutter (Dahkki), Marie-Isabel eAguilar (Dahkki)
• Materiálatiipa: Girji
• Almmustuhtton: Frontiers Media S.A., 2015-01-01T00:00:00Z.
• Fáttát: article
• Liŋkkat: Connect to this object online.

Angiotensin converting enzyme 2 (ACE2) is a zinc carboxypeptidase involved in the renin angiotensin system (RAS) and inactivates the potent vasopressive peptide angiotensin II (Ang II) by removing the C-terminal phenylalanine residue to yield Ang1-7. This conversion inactivates the vasoconstrictive...