Identification of Ascorbic Acid and Gallic Acid as Novel Inhibitors of Secreted Frizzled-Related Protein for the Treatment of Obesity-Induced Type 2 Diabetes

• Main Authors: Shazia Anwer Bukhari (Author), Aysha Yasmin (Author), Azhar Rasul (Author), Muhammad Asif Zahoor (Author), Ghulam Mustafa (Author), Dunia A. Al Farraj (Author), Noura M. Darwish (Author), Lotfi Aleya (Author), Asim Rehman (Author)
• Format: Book
• Published: SAGE Publishing, 2022-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Type 2 diabetes mellitus (T2D) has been reported as major public health issue rising at an alarming rate worldwide, and obesity is the leading risk factor for the development of T2D. Secreted frizzled-related protein 4 ( SFRP4 ) released with inflammatory mediators from adipose tissues constrains th...