Anti-tumor effect of local injectable hydrogel-loaded endostatin alone and in combination with radiotherapy for lung cancer

• Main Authors: Na Wang (Author), Qin Gao (Author), Juan Tang (Author), YiQing Jiang (Author), LiShi Yang (Author), XiangXiang Shi (Author), Yue Chen (Author), Yan Zhang (Author), ShaoZhi Fu (Author), Sheng Lin (Author)
• Format: Book
• Published: Taylor & Francis Group, 2021-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Endostatin (ES) can effectively inhibit neovascularization in most solid tumors and has the potential to make oxygen delivery more efficient and increase the efficacy of radiotherapy (RT). With a short half-life, ES is mainly administered systemically, which leads to low intake in tumor tissue and o...