Determination of lamotrigine in human plasma using liquid chromatography‐tandem mass spectrometry

• Main Authors: Shogo Itabashi (Author), Rina Bito (Author), Maika Nishina (Author), Maki Fukumoto (Author), Midori Soda (Author), Mitsunori Doi (Author), Shigeyuki Usui (Author), Kiyoyuki Kitaichi (Author)
• Format: Book
• Published: Wiley, 2019-03-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract Aim Lamotrigine (LTG) is a widely used anti‐epileptic drug that is administered to avoid seizures and to maintain seizure‐free status. However, several factors reportedly cause individual differences of plasma LTG levels, and the therapeutic target range of LTG varies between individuals. T...