Novel indole derivatives as hepatitis C virus NS5B polymerase inhibitors: Pharmacophore modeling and 3D QSAR studies

Hepatitis C Virus (HCV) encodes its own RNA dependent RNA polymerase (NS5b) in order to replicate its genome. An efficient pharmacophore was identified, by executing structural analysis of a set of 49 indole-based inhibitors of the HCV NS5B polymerase. Identified pharmacophoric features, two hydroph...

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Bibliographic Details
Main Authors: G. Varun (Author), M. Lokesh (Author), M. Sandeep (Author), Sajad Shahbazi (Author), Deepak Reddy Gade (Author)
Format: Book
Published: Bangladesh Pharmacological Society, 2014-07-01T00:00:00Z.
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3rd Floor Main Library

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Call Number: A1234.567
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