G9a promotes muscular atrophy in chronic aging and acute denervation

• Main Authors: Ying Jin (Author), Wei Kang (Author), Xiaoge Ji (Author), Yihao Zhou (Author), Ling Zheng (Author)
• Format: Knjiga
• Izdano: BMC, 2024-11-01T00:00:00Z.
• Teme: article
• Online dostop: Connect to this object online.

Abstract Muscular atrophy accompanied by neuromuscular junction (NMJ) denervation is often observed after long-term chronic diseases and aging and is associated with substantial morbidity and mortality. Here, we report that histone methyltransferase G9a is elevated in the muscle of muscular atrophy...