Inhibition of p300 by Garcinol Protects against Cisplatin-Induced Acute Kidney Injury through Suppression of Oxidative Stress, Inflammation, and Tubular Cell Death in Mice

Emerging evidence suggests that epigenetic mechanisms such as histone modification are crucially involved in the pathophysiology of acute kidney injury (AKI). The histone acetyltransferase p300 regulates several biological processes through the acetylation of histones or transcription factors. Howev...

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Главные авторы: Jung-Yeon Kim (Автор), Jungmin Jo (Автор), Jaechan Leem (Автор), Kwan-Kyu Park (Автор)
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Опубликовано: MDPI AG, 2020-12-01T00:00:00Z.
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