Strength of clinical evidence leading to approval of novel cancer medicines in Europe: A systematic review and data synthesis

• Main Authors: Alberto Farina (Author), Federico Moro (Author), Frederick Fasslrinner (Author), Annahita Sedghi (Author), Miluska Bromley (Author), Timo Siepmann (Author)
• Format: Book
• Published: Wiley, 2021-08-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract We aimed to evaluate the quality of clinical evidence that substantiated approval of cancer medicines by the European Medicines Agency (EMA) in the last decade. We performed a systematic review and data synthesis of EMA documents in agreement with PRISMA guidelines. We included the European...