Modular Assembly of Cell-targeting Devices Based on an Uncommon G-quadruplex Aptamer

• Main Authors: Felipe Opazo (Author), Laura Eiden (Author), Line Hansen (Author), Falk Rohrbach (Author), Jesper Wengel (Author), Jørgen Kjems (Author), Günter Mayer (Author)
• Format: Book
• Published: Elsevier, 2015-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Aptamers are valuable tools that provide great potential to develop cost-effective diagnostics and therapies in the biomedical field. Here, we report a novel DNA aptamer that folds into an unconventional G-quadruplex structure able to recognize and enter specifically into human Burkitt's lympho...