Cepharanthine inhibits influenza A virus replication by impairing viral polymerase activity and regulating influenza-induced immune response

• Váldodahkkit: Yinyan Li (Dahkki), Huiting Sang (Dahkki), Qinxian Mo (Dahkki), Linrui Jiang (Dahkki), Zhixuan Chen (Dahkki), Jinlong Liang (Dahkki), Chunyu Zhang (Dahkki), Zhengyin Zhang (Dahkki), Chenglai Xia (Dahkki), Jie Yang (Dahkki)
• Materiálatiipa: Girji
• Almmustuhtton: Elsevier, 2024-05-01T00:00:00Z.
• Fáttát: article
• Liŋkkat: Connect to this object online.

Background: Cepharanthine (CEP), a natural bis-benzylisoquinoline alkaloid extracted from the plant Stephania cephalantha Hayata, has been widely used to treat several acute and chronic diseases. However, its antiviral potential against influenza A virus (IAV) infection remains unknown. Purpose: The...