Mobilized Peripheral Blood versus Cord Blood: Insight into the Distinct Role of Proinflammatory Cytokines on Survival, Clonogenic Ability, and Migration of CD34+ Cells

• Main Authors: Dorian Forte (Author), Daria Sollazzo (Author), Martina Barone (Author), Marisole Allegri (Author), Angela di Martella Orsi (Author), Marco Romano (Author), Barbara Sinigaglia (Author), Giuseppe Auteri (Author), Nicola Vianelli (Author), Michele Cavo (Author), Francesca Palandri (Author), Lucia Catani (Author)
• Format: Book
• Published: Hindawi Limited, 2018-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Inflammation may play a role in cancer. However, the contribution of cytokine-mediated crosstalk between normal hemopoietic stem/progenitor cells (HSPCs) and their (inflammatory) microenvironment is largely elusive. Here we compared survival, phenotype, and function of neonatal (umbilical cord blood...