A logic "OR" gate composed of a blue light‐induced CRISPR/dCas9 system and a Tet‐on system activates cancer suppressor genes to inhibit the growth of cutaneous squamous cell carcinoma cells

A logic "OR" gate composed of a blue light‐induced CRISPR/dCas9 system and a Tet‐on system activates cancer suppressor genes to inhibit the growth of cutaneous squamous cell carcinoma cells

Abstract Optogenetic systems and tetracycline‐induced expression systems have been used in biological research. In gene circuits, light and tetracycline are often used to control the activation or inhibition of gene expression. In our study, we used a blue light induction system and tetracycline ind...

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Main Authors: Xinbo Huang (Author), Jieyi Wang (Author), Xia Wu (Author), Bin Jiang (Author), Menghui Chen (Author), Han Chen (Author), Yan Mao (Author), Cheng zhou (Author), Bo Yu (Author)
Format: Book
Published: Wiley, 2022-12-01T00:00:00Z.
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