Evaluation of β1L-Adrenoceptors in Rabbit Heart by Tissue Segment Binding Assay

• Main Authors: Hatsumi Yoshiki (Author), Atsushi Nishimune (Author), Fumiko Suzuki (Author), Shigeru Morishima (Author), Takeshi Ikeda (Author), Masato Sasaki (Author), Leslie M. Audigane (Author), Chantal Gauthier (Author), Ikunobu Muramatsu (Author)
• Format: Book
• Published: Elsevier, 2009-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract.: [3H]-CGP12177 biphasically bound to β-adrenoceptors with high and low affinities in the segments and crude membranes of rabbit left ventricle. The low-affinity sites for [3H]-CGP12177 in the segments was double in density, compared to the density of high-affinity sites. Total abundance of...