Potential regulatory role of the Nrf2/HMGB1/TLR4/NF-κB signaling pathway in lupus nephritis

• Main Authors: Shi-jie Li (Author), Dan-dan Ruan (Author), Wei-zhen Wu (Author), Min Wu (Author), Qiu-yan Wu (Author), Han-lu Wang (Author), Yuan-yuan Ji (Author), Yan-ping Zhang (Author), Xin-fu Lin (Author), Zhu-ting Fang (Author), Li-sheng Liao (Author), Jie-wei Luo (Author), Mei-zhu Gao (Author), Jia-bin Wu (Author)
• Format: Book
• Published: BMC, 2023-10-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract Objectives Systemic lupus erythematosus is an autoimmune disease that involves multiple organ systems. One of its major complications, lupus nephritis (LN), is associated with a high mortality rate, and children-onset LN have a more severe course and worse prognosis than adults. Oxidative s...