Ginger Polyphenols Reverse Molecular Signature of Amygdala Neuroimmune Signaling and Modulate Microbiome in Male Rats with Neuropathic Pain: Evidence for Microbiota-Gut-Brain Axis

• Main Authors: Chwan-Li Shen (Author), Julianna Maria Santos (Author), Moamen M. Elmassry (Author), Viren Bhakta (Author), Zarek Driver (Author), Guangchen Ji (Author), Vadim Yakhnitsa (Author), Takaki Kiritoshi (Author), Jacob Lovett (Author), Abdul Naji Hamood (Author), Shengmin Sang (Author), Volker Neugebauer (Author)
• Format: Book
• Published: MDPI AG, 2024-04-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Emerging evidence shows that the gut microbiota plays an important role in neuropathic pain (NP) via the gut-brain axis. Male rats were divided into sham, spinal nerve ligation (SNL), SNL + 200 mg GEG/kg BW (GEG200), and SNL + 600 mg GEG/kg BW (GEG600) for 5 weeks. The dosages of 200 and 600 mg GEG/...