Effect of naftopidil on brain noradrenaline-induced decrease in arginine-vasopressin secretion in rats

• Main Authors: Masaki Yamamoto (Author), Takahiro Shimizu (Author), Shogo Shimizu (Author), Youichirou Higashi (Author), Kumiko Nakamura (Author), Mikiya Fujieda (Author), Motoaki Saito (Author)
• Format: Book
• Published: Elsevier, 2016-09-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Naftopidil, an α1-adrenoceptor antagonist, has been shown to inhibit nocturnal polyuria in patients with lower urinary tract symptom. However, it remains unclear how naftopidil decreases nocturnal urine production. Here, we investigated the effects of naftopidil on arginine-vasopressin (AVP) plasma...