Influence of Formulation Parameters on Redispersibility of Naproxen Nanoparticles from Granules Produced in a Fluidized Bed Process

• Main Authors: Martin Wewers (Author), Stefan Czyz (Author), Jan Henrik Finke (Author), Edgar John (Author), Bernard Van Eerdenbrugh (Author), Michael Juhnke (Author), Heike Bunjes (Author), Arno Kwade (Author)
• Format: Book
• Published: MDPI AG, 2020-04-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

The particle size reduction of active pharmaceutical ingredients is an efficient method to overcome challenges associated with a poor aqueous solubility. With respect to stability and patient's convenience, the corresponding nanosuspensions are often further processed to solid dosage forms. In...