Varenicline aggravates atherosclerotic plaque formation in nicotine-pretreated ApoE knockout mice due to enhanced oxLDL uptake by macrophages through downregulation of ABCA1 and ABCG1 expression

Varenicline aggravates atherosclerotic plaque formation in nicotine-pretreated ApoE knockout mice due to enhanced oxLDL uptake by macrophages through downregulation of ABCA1 and ABCG1 expression

Varenicline is a widely used and effective drug for smoking cessation. We previously reported that varenicline aggravates atherosclerosis in apolipoprotein E knockout (ApoE KO) mice. However, it remains unknown whether varenicline affects cardiovascular events in patients with nicotine addiction. He...

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Main Authors: Mitsuhisa Koga (Author), Yuki Kanaoka (Author), Mana Okamoto (Author), Yuki Nakao (Author), Koshun Inada (Author), Saki Takayama (Author), Yasufumi Kataoka (Author), Atsushi Yamauchi (Author)
Format: Book
Published: Elsevier, 2020-01-01T00:00:00Z.
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