Isorhamnetin Inhibits Human Gallbladder Cancer Cell Proliferation and Metastasis via PI3K/AKT Signaling Pathway Inactivation

• Main Authors: Tianyu Zhai (Author), Xiaoyu Zhang (Author), Zhenyu Hei (Author), Longyang Jin (Author), Chao Han (Author), Audrey Tsznam Ko (Author), Xiaofeng Yu (Author), Jiandong Wang (Author)
• Format: Book
• Published: Frontiers Media S.A., 2021-02-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Gallbladder cancer (GBC) is the most common biliary tract tumor with a poor prognosis. Isorhamnetin is a flavonoid compound extracted from Hippophae rhamnoides L. and has several pharmacological effects including anti-inflammatory and anti-cancer properties. We treated GBC-SD and NOZ of GBC cell lin...