Effects of Pirfenidone and Nintedanib on Markers of Systemic Oxidative Stress and Inflammation in Patients with Idiopathic Pulmonary Fibrosis: A Preliminary Report

• Hoofdauteurs: Alessandro G. Fois (Auteur), Elisabetta Sotgiu (Auteur), Valentina Scano (Auteur), Silvia Negri (Auteur), Sabrina Mellino (Auteur), Elisabetta Zinellu (Auteur), Pietro Pirina (Auteur), Gianfranco Pintus (Auteur), Ciriaco Carru (Auteur), Arduino A. Mangoni (Auteur), Angelo Zinellu (Auteur)
• Formaat: Boek
• Gepubliceerd in: MDPI AG, 2020-10-01T00:00:00Z.
• Onderwerpen: article
• Online toegang: Connect to this object online.

Introduction: In vitro evidence suggests that pirfenidone and nintedanib, approved agents for the treatment of idiopathic pulmonary fibrosis (IPF), exert anti-inflammatory and anti-oxidant effects. We aimed to investigate such effects in vivo in IPF patients. Methods: Systemic circulating markers of...