Effects of Pirfenidone and Nintedanib on Markers of Systemic Oxidative Stress and Inflammation in Patients with Idiopathic Pulmonary Fibrosis: A Preliminary Report

• मुख्य लेखकों: Alessandro G. Fois (लेखक), Elisabetta Sotgiu (लेखक), Valentina Scano (लेखक), Silvia Negri (लेखक), Sabrina Mellino (लेखक), Elisabetta Zinellu (लेखक), Pietro Pirina (लेखक), Gianfranco Pintus (लेखक), Ciriaco Carru (लेखक), Arduino A. Mangoni (लेखक), Angelo Zinellu (लेखक)
• स्वरूप: पुस्तक
• प्रकाशित: MDPI AG, 2020-10-01T00:00:00Z.
• विषय: article
• ऑनलाइन पहुंच: Connect to this object online.

Introduction: In vitro evidence suggests that pirfenidone and nintedanib, approved agents for the treatment of idiopathic pulmonary fibrosis (IPF), exert anti-inflammatory and anti-oxidant effects. We aimed to investigate such effects in vivo in IPF patients. Methods: Systemic circulating markers of...