FGF4 protects the liver from immune-mediated injury by activating CaMKKβ-PINK1 signal pathway to inhibit hepatocellular apoptosis

• Main Authors: Zhifeng Huang (Author), Tongtong Pan (Author), Liang Xu (Author), Lu Shi (Author), Xiong Ma (Author), Liya Zhou (Author), Luyao Wang (Author), Jiaojiao Wang (Author), Guoqing Zhu (Author), Dazhi Chen (Author), Lingtao Song (Author), Xiaomin Pan (Author), Xiaodong Wang (Author), Xiaokun Li (Author), Yongde Luo (Author), Yongping Chen (Author)
• Format: Book
• Published: Elsevier, 2024-04-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Immune-mediated liver injury (ILI) is a condition where an aberrant immune response due to various triggers causes the destruction of hepatocytes. Fibroblast growth factor 4 (FGF4) was recently identified as a hepatoprotective cytokine; however, its role in ILI remains unclear. In patients with auto...