Variability of Tacrolimus Trough Concentration in Liver Transplant Patients: Which Role of Inflammation?

• Main Authors: Anaelle Chavant (Author), Xavier Fonrose (Author), Elodie Gautier-Veyret (Author), Marie Noelle Hilleret (Author), Matthieu Roustit (Author), Francoise Stanke-Labesque (Author)
• Format: Book
• Published: MDPI AG, 2021-11-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Tacrolimus presents high intra and inter-individual variability in its blood trough concentration (Cmin). Knowledge of the factors that are involved in tacrolimus Cmin variability is thus clinically important to prevent or limit it. Inflammation can affect the pharmacokinetic properties of drugs. We...