MSCs-derived apoptotic extracellular vesicles promote muscle regeneration by inducing Pannexin 1 channel-dependent creatine release by myoblasts

• Main Authors: Qingyuan Ye (Author), Xinyu Qiu (Author), Jinjin Wang (Author), Boya Xu (Author), Yuting Su (Author), Chenxi Zheng (Author), Linyuan Gui (Author), Lu Yu (Author), Huijuan Kuang (Author), Huan Liu (Author), Xiaoning He (Author), Zhiwei Ma (Author), Qintao Wang (Author), Yan Jin (Author)
• Format: Book
• Published: Nature Publishing Group, 2023-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract Severe muscle injury is hard to heal and always results in a poor prognosis. Recent studies found that extracellular vesicle-based therapy has promising prospects for regeneration medicine, however, whether extracellular vesicles have therapeutic effects on severe muscle injury is still unk...