Development, Testing, Parameterisation and Calibration of a Human PBPK Model for the Plasticiser, Di-(2-propylheptyl) Phthalate (DPHP) Using in Silico, in vitro and Human Biomonitoring Data

A physiologically based pharmacokinetic model for Di-(2-propylheptyl) phthalate (DPHP) was developed to interpret the biokinetics in humans after single oral doses. The model was parameterized with in vitro and in silico derived parameters and uncertainty and sensitivity analysis was used during the...

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Main Authors: Kevin McNally (Author), Craig Sams (Author), Alex Hogg (Author), Annie Lumen (Author), George Loizou (Author)
Format: Book
Published: Frontiers Media S.A., 2021-09-01T00:00:00Z.
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3rd Floor Main Library

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Call Number: A1234.567
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