Insertion Process of Ceramic Nanoporous Microneedles by Means of a Novel Mechanical Applicator Design

• Main Authors: Xavier H. M. Hartmann (Author), Peter van der Linde (Author), Erik F. G. A. Homburg (Author), Lambert C. A. van Breemen (Author), Arthur M. de Jong (Author), Regina Luttge (Author)
• Format: Book
• Published: MDPI AG, 2015-11-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Arrays of microneedles (MNAs) are integrated in an out-of-plane fashion with a base plate and can serve as patches for the release of drugs and vaccines. We used soft-lithography and micromolding to manufacture ceramic nanoporous (np)MNAs. Failure modes of ceramic npMNAs are as yet poorly understood...