Donepezil structure-based hybrids as potential multifunctional anti-Alzheimer's drug candidates

• প্রধান লেখক: Luca Piemontese (লেখক), Daniel Tomás (লেখক), Asha Hiremathad (লেখক), Vito Capriati (লেখক), Emanuel Candeias (লেখক), Sandra M. Cardoso (লেখক), Sílvia Chaves (লেখক), M. Amélia Santos (লেখক)
• বিন্যাস: গ্রন্থ
• প্রকাশিত: Taylor & Francis Group, 2018-01-01T00:00:00Z.
• বিষয়গুলি: article
• অনলাইন ব্যবহার করুন: Connect to this object online.

A new series of multifunctional hybrids, based on the structure of the donepezil (DNP) drug, have been developed and evaluated as potential anti Alzheimer's disease (AD) agents. The rationale of this study was the conjugation of a benzylpiperidine/benzylpiperazine moiety with derivatives of bio...