Donepezil structure-based hybrids as potential multifunctional anti-Alzheimer's drug candidates

• मुख्य लेखकों: Luca Piemontese (लेखक), Daniel Tomás (लेखक), Asha Hiremathad (लेखक), Vito Capriati (लेखक), Emanuel Candeias (लेखक), Sandra M. Cardoso (लेखक), Sílvia Chaves (लेखक), M. Amélia Santos (लेखक)
• स्वरूप: पुस्तक
• प्रकाशित: Taylor & Francis Group, 2018-01-01T00:00:00Z.
• विषय: article
• ऑनलाइन पहुंच: Connect to this object online.

A new series of multifunctional hybrids, based on the structure of the donepezil (DNP) drug, have been developed and evaluated as potential anti Alzheimer's disease (AD) agents. The rationale of this study was the conjugation of a benzylpiperidine/benzylpiperazine moiety with derivatives of bio...