Usefulness of Bnet, a Simple Linear Metric in Discerning Torsades De Pointes Risks in 28 CiPA Drugs

The Comprehensive in vitro Proarrhythmia Assay (CiPA) project suggested the torsade metric score (TMS) which requires substantial computing resources as a useful biomarker to predict proarrhythmic risk from human ether-à-go-go-related gene (hERG) and a few other ion channel block data. The TMS was u...

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Main Authors: Sungpil Han (Author), Seunghoon Han (Author), Ki-Suk Kim (Author), Hyang-Ae Lee (Author), Dong-Seok Yim (Author)
Format: Book
Published: Frontiers Media S.A., 2019-11-01T00:00:00Z.
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3rd Floor Main Library

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Call Number: A1234.567
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