Variability of efavirenz plasma concentrations among pediatric HIV patients treated with efavirenz based combination antiretroviral therapy in Dar es Salaam, Tanzania

• Hauptverfasser: Selemani Saidi Sungi (Verfasst von), Eliford Ngaimisi (Verfasst von), Nzovu Ulenga (Verfasst von), Philip Sasi (Verfasst von), Sabina Mugusi (Verfasst von)
• Format: Buch
• Veröffentlicht: BMC, 2018-10-01T00:00:00Z.
• Schlagworte: article
• Online-Zugang: Connect to this object online.

Abstract Background Children are subject to varying drug pharmacokinetics which influence plasma drug levels, and hence treatment outcomes especially for drugs like efavirenz whose plasma concentrations are directly related to treatment outcomes. This study is aimed at determining plasma efavirenz c...