Ivermectin as an adjuvant to anti-epileptic treatment in persons with onchocerciasis-associated epilepsy: A randomized proof-of-concept clinical trial.

• Main Authors: Michel Mandro (Author), Joseph Nelson Siewe Fodjo (Author), Deby Mukendi (Author), Alfred Dusabimana (Author), Sonia Menon (Author), Steven Haesendonckx (Author), Richard Lokonda (Author), Swabra Nakato (Author), Francoise Nyisi (Author), Germain Abhafule (Author), Deogratias Wonya'Rossi (Author), Jean Marie Jakwong (Author), Patrick Suykerbuyk (Author), Jacques Meganck (Author), An Hotterbeekx (Author), Robert Colebunders (Author)
• Format: Book
• Published: Public Library of Science (PLoS), 2020-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

INTRODUCTION:Recent findings from onchocerciasis-endemic foci uphold that increasing ivermectin coverage reduces the epilepsy incidence, and anecdotal evidence suggests seizure frequency reduction in persons with onchocerciasis-associated epilepsy, when treated with ivermectin. We conducted a random...