Expression levels of the selenium-uptake receptor LRP8, the antioxidant selenoprotein GPX1 and steroidogenic enzymes correlate in granulosa cells

• Main Authors: Katja Hummitzsch (Author), Jasmine E Kelly (Author), Nicholas Hatzirodos (Author), Wendy M Bonner (Author), Feng Tang (Author), Hugh H Harris (Author), Raymond J Rodgers (Author)
• Format: Book
• Published: Bioscientifica, 2024-08-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Reactive oxygen species (ROS) are a by-product of the activity of cytochrome P450 steroidogenic enzymes. Antioxidant enzymes protect against ROS damage. To identify if any particular antioxidant enzyme is used to protect against ROS produced by granulosa cells as follicles enlarge and produce oestra...