A recombinant multi-epitope protein MEP1 elicits efficient long-term immune responses against HIV-1 infection

• Main Authors: Yi Yang (Author), Qing Zhu (Author), Weilai Sun (Author), Jingjing Guo (Author), Xiuzhe Ning (Author), Qiao Li (Author), Yan Guo (Author), Junfeng Li (Author), Zhihua Kou (Author), Yusen Zhou (Author)
• Format: Book
• Published: Taylor & Francis Group, 2017-06-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

The effective protective HIV vaccine should elicit either protective antibodies or effective T cell response, or both. To improve the efficacy of HIV-1 vaccines, HLA polymorphism and HIV-1 diversity are 2 key factors to be considered for vaccine development. In this study, we expressed a recombinant...