Dexmedetomidine Inhibits Voltage-Gated Sodium Channels via α2-Adrenoceptors in Trigeminal Ganglion Neurons

• Váldodahkkit: Sang-Taek Im (Dahkki), Youn Yi Jo (Dahkki), Gayoung Han (Dahkki), Hyun Jung Jo (Dahkki), Yong Ho Kim (Dahkki), Chul-Kyu Park (Dahkki)
• Materiálatiipa: Girji
• Almmustuhtton: Hindawi Limited, 2018-01-01T00:00:00Z.
• Fáttát: article
• Liŋkkat: Connect to this object online.

Dexmedetomidine, an α2-adrenoceptor agonist, is widely used as a sedative and analgesic agent in a number of clinical applications. However, little is known about the mechanism by which it exerts its analgesic effects on the trigeminal system. Two types of voltage-gated sodium channels, Nav1.7 and N...