Effects of Flow Hydrodynamics and Eye Movements on Intraocular Drug Clearance

• المؤلفون الرئيسيون: Angeliki Velentza-Almpani (مؤلف), Nkiruka Ibeanu (مؤلف), Tianyang Liu (مؤلف), Christopher Redhead (مؤلف), Peng Tee Khaw (مؤلف), Steve Brocchini (مؤلف), Sahar Awwad (مؤلف), Yann Bouremel (مؤلف)
• التنسيق: كتاب
• منشور في: MDPI AG, 2022-06-01T00:00:00Z.
• الموضوعات: article
• الوصول للمادة أونلاين: Connect to this object online.

New in vitro prototypes (PK-Eye™) were tested with and without eye movement to understand diffusion and convection effects on intraocular clearance. Port placement in front ((i) ciliary inflow model) and behind the model lens ((ii) posterior inflow model) was used to study bevacizumab (1.25 mg/50 µL...