Factors Influencing the Steady-State Plasma Concentration of Imatinib Mesylate in Patients With Gastrointestinal Stromal Tumors and Chronic Myeloid Leukemia

Imatinib mesylate (IM) is the standard treatment for advanced, metastatic gastrointestinal stromal tumors (GISTs) and chronic myeloid leukemia (CML) with a fixed daily standard dosage via the oral route. Interindividual and intraindividual variability in plasma concentrations have been closely linke...

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Main Authors: Yan Chen (Author), Xiuhua Dong (Author), QiuJu Wang (Author), ZhiXi Liu (Author), XinWei Dong (Author), Sanjun Shi (Author), HongTao Xiao (Author)
Format: Book
Published: Frontiers Media S.A., 2020-11-01T00:00:00Z.
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